2025 Lexus LX 600 vs 2025 Mercedes Benz Gls 580 4MATIC By Billy G. · Founder & Lead Editor
2025 Lexus LX
2025 Lexus LX 600
vs
2025 Mercedes Benz
2025 Mercedes Benz Gls 580 4MATIC
The 2025 Lexus LX 600 and the 2025 Mercedes-Benz GLS 580 4MATIC both position themselves as full-size luxury SUVs that blend off-road capability with substantial on-road comfort, yet they diverge in meaningful ways according to published specifications and owner-reported reliability data. The Lexus LX 600 emphasizes body-on-frame construction, a twin-turbo V6 producing 409 horsepower. And standard four-wheel drive with low-range gearing, while the Mercedes-Benz GLS 580 4MATIC relies on an unibody platform, a mild-hybrid 4.0-liter V8 delivering 510 horsepower, and an advanced air suspension system tuned for highway refinement. Public reviews consistently note the LX 600’s stronger resale retention. And higher ground clearance, whereas the GLS 580 4MATIC draws praise for its lower reported recall count and quieter cabin at sustained speeds. Fuel economy figures released by Lexus list the LX 600 at a combined 19 mpg with an estimated annual fuel cost of $4,350; Mercedes has not published equivalent combined MPG or annual cost data for the GLS 580 4MATIC. Bottom line: buyers prioritizing proven durability and explicit efficiency numbers may lean toward the Lexus, while those seeking higher output and fewer official recalls often favor the Mercedes-Benz.
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